аЯрЁБс;ўџ 63ўџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџ§џџџџџџџ  !"#$%&'()*+,-./012ўџџџўџџџ5ўџџџ7ўџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџRoot Entryџџџџџџџџџџџџўџџџџџџџџџџџџџџџўџџџџџџџџџџџџџџџўџџџџџџџџџџџџџџџўџџџ Л ЬсАСт\pCalc BАaР= œЏМ=@ 8X@"Зк1мCalibri1ШџArial1ШџArial1ШџArial1мМCalibri ЄGeneral;Ѕ6_(\$* #,##0.00_);_(\$* \(#,##0.00\);_(\$* \-??_);_(@_) І#,##0 Ї#,##0.00рЄѕџ Р рѕџ єР рѕџ єР рѕџ єР рѕџ єР рѕџ єР рѕџ єР рѕџ єР рѕџ єР рѕџ єР рѕџ єР рѕџ єР рѕџ єР рѕџ єР рѕџ єР рЄ Р р+ѕџ №Р р)ѕџ №Р р,ѕџ №Р р*ѕџ №Р р ѕџ №Р рЄ (Р рЄ"8Р рЄ*8Р рЄ (Р рЄ"8Р рЅ $Р рІ $Р рЇ $Р рЄ Р рЄ#0Р “€џ“€џ“€џ“€џ“€џ“€џ`…"†calculation of registratio…Ђ!item 8 exhibits…t+2022 inducement plan…–/2022 inducement plan-1…45notice of exercise…Z= lockup period…Р?2022 inducement plan-2…E2022 inducement plan-3…"žJadditional termsacknowledg…|Qnotice of exercise-1…dTshares…[shares-1…†^lockup period-1ŒССTыК№В№x4      3 №П Р@@ё  їќФŒbCALCULATION OF REGISTRATION FEE%Title of Securities to be RegisteredAmount to be Registered (1))Proposed Maximum Offering Price per Share)Proposed Maximum Aggregate Offering PriceAmount of Registration Fee(Common Stock, par value $0.001 per share 2018 Equity Incentive Plan 1,927,624 (2) $2.34 (4)# 2018 Employee Stock Purchase Plan 481,906 (3) $1.99 (5) Inducement Plan $2.34 (6)TotalItem 8. Exhibits.Incorporated by ReferenceExhibit NumberDescription of Document Schedule/Form File NumberExhibit Filing Date\Amended and Restated Certificate of Incorporation of the Registrant, as currently in effect.8-K 001-38697October 22, 2018FAmended and Restated Bylaws of the Registrant, as currently in effect.S-1/A 333-227474October 5, 20185.1*Opinion of Cooley LLP23.1*BConsent of KPMG LLP, independent registered public accounting firm23.2*/Consent of Cooley LLP (included in Exhibit 5.1)24.1*CPower of Attorney (included on the signature page of this Form S-8)o2018 Equity Incentive Plan, as amended, and Forms of Stock Option Grant Notice and Option Agreements thereunder10-QNovember 10, 2021!2018 Employee Stock Purchase PlanS-8 333-22793599.3*\2022 Inducement Plan and Forms of Stock Option Grant Notice and Option Agreements thereunder(2022 INDUCEMENT PLAN) Optionholder:Date of Grant:Vesting Commencement Date:#Number of Shares Subject to Option:Exercise Price (Per Share):Total Exercise Price:Expiration Date:Exercise Schedule :Same as Vesting ScheduleVesting Schedule :5[ One-fourth (1/4th) of the shares vest one year after the Vesting Commencement Date; the balance of the shares vest in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date], subject to Optionholder s Continuous Service as of each such datePayment:SBy one or a combination of the following items (described in the Option Agreement):C& By cash, check, bank draft or money order payable to the CompanyF& Pursuant to a Regulation T Program if the shares are publicly tradedG& By delivery of already-owned shares if the shares are publicly traded[& Subject to the Company s consent at the time of exercise, by a  net exercise arrangementNOTICE OF EXERCISEStock option dated:1Number of Shares as to which option is exercised:%Certificates to be issued in name of:Total exercise price:$$ Cash payment delivered herewith:0[Value of ________ Shares delivered herewith 1 :]3[Value of ________ Shares pursuant to net exercise:-[Regulation T Program (cashless exercise 3 ):Lock-Up PeriodVery truly yours,Exercise Schedule:Vesting Schedule:Š[One-fourth (1/4th) of the shares vest one year after the Vesting Commencement Date; the balance of the shares vest in a series of 36 successive equal monthly installments measured from the first anniversary of the Vesting Commencement Date,] subject to Optionholder s Continuous Service as of each such date and the potential vesting acceleration described in Section 1 of the Option AgreementG& Pursuant to a Regulation T Program if the shares are publicly tradedH& By delivery of already-owned shares if the shares are publicly traded\& Subject to the Company s consent at the time of exercise, by a  net exercise arrangement"Additional Terms/Acknowledgements:PHASEBIO PHARMACEUTICALS, INC. OPTIONHOLDER:By: SignatureTitle:Date: 1 Great Valley Parkway, Suite 30!Date of Exercise: _______________Malvern, Pennsylvania 19355Shares$______________6[Value of ________ Shares pursuant to net exercise 2 :џ bŸ cc Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А , @,,,, ,§ О§ О § О § О §  О   §  О  § О"§ О § О §  О ~  CУŠkО   ~  [О  §  О §  О §  О ~  {:нО   ~  ыŠО  §  О ~ sUО § О ~  ‚ѓЧО   ~  ‡кО  § О ~ ъƒшО  333#TЎ`AО  ~ ЧђО хњ              ьP№H№№0№( № №>Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А,,,,,, , , , , ,,§ ОО§  О § О § О § О §  О   §  О  § О ffffff@О § О § О §  О   ~  лО  § О ~ “О § О § О §  О   ~  SО  § О §  О § !О"§ "О § #О" § $О § %О" § &О § 'О" ~ лšО § (О § )О § О  ~ ЫО § *О ~ ›О § +О § ,О § -О  ~ О § О § .О § /О"х A                                    ьP№H №№0№( № №>Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А , , , , , , , ,§ 0О§ 1О§ 2О§ 3О§ 4О§ 5О§ 6О § 7О хВ      ьP№H0№ №0№( № № >Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А ,,,,,,, , , ,§ 8О§ 9ОО$§ :О§ ;ОО$§ <О§ =ОО$О§ >ОО § ?О О § @О О § AО хђ           ьP№H@№№0№( № №>Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А ,,,,,, , , , ,§ BОО<§ CО:§ DО:§ EО:§ FО"§ GО§ HО" § GО § IО" § GО § JО § KО" § GО § JО § LО" § GО § JО хjM                                      ьP№HP№№0№( № №>Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А,,,,§ MО§ NО О О х"ьP№H`№№0№( № №>Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А ,,,,,, , ,§ 0О§ 1О(§ 2О(§ 3О(§ 4О(§ 5О(§ 6О( § 7О( хZ+                    ьP№Hp№№0№( № №>Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А ,,,,,,, , , ,§ OО§ 9ОО$§ PО§ QОО$§ <О§ =ОО$О§ >ОО § RО О § SО О § TО хъ           ьP№H€№ №0№( № № >Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А ,,,,,, , , ,§ UОО<§ VО(§ WОО<§ XО:О§ YО(§ YО О< § ZО( § [О § [О: хъ=                              ьP№H№$№0№( № №$>Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А , , , ,§ BО§ VО§ \О§ ]О § ^ОхR ьP№H №(№0№( № №(>Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А ,,,,,, , , , ,§ _ОО0§ CО.О0§ DО.О0§ EО. О0 § FО § `О  § `О § HО § `О  § `О хв:                              ьP№HА№,№0№( № №,>Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А,,,§ IО § `О §  `О § aО § `О §  `О § LО § `О §  `О хz         ьP№HР№0№0№( № №0>Ж@<dggџџџџ Л Ь d-Cыт6?_€%,С*+‚ƒ„&ffffffц?'ffffffц?(ш?)ш?Ё"d,, Ж` Ж`р? Ж` Ж`р?U} А,,,,§ MО§ NО О О х"ьP№Hа№4№0№( № №4>Ж@<dggџџџџ ўџџџўџџџўџџџ ўџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџџўџ џџџџРFMicrosoft Excel 97-TabelleBiff8ўџр…ŸђљOhЋ‘+'Гй0|8 @ L X d pщ§0@@@}ж0Х и@}ж0Х иўџеЭеœ.“—+,љЎDеЭеœ.“—+,љЎ\щ§ HШарьєќ AppVersion DocSecurityHyperlinksChangedLinksUpToDate ScaleCrop ShareDocщ§12.0000 Root EntryџџџџџџџџРF4Workbookџџџџь`CompObjџџџџџџџџIOle џџџџџџџџџџџџSummaryInformation(џџџџџџџџЌDocumentSummaryInformation8џџџџџџџџџџџџhџџџџџџџџџџџџўџџџџџџџџџџџџџџџўџџџ